Child with lupus
- In contrast to other autoimmune diseases, there
is universally no maximum age up to when pediatric SLE rather than adult SLE is
diagnosed. The disease onset is much more aggressive with a higher frequency of
major organ involvement at the time of diagnosis.
- Lupus presents
in childhood in 15% – 20% of cases. SLE is rare in children although around 20%
of all cases of SLE will have onset before adulthood.
- The
incidence of cSLE is reported to
be 630 per
100 000 children per
year.
- In cSLE,
the female to male ratio is around 5 :1 in contrast to the 9 :1 ratio seen in
adults.
- Five year
survival is currently between 90% and 95%.
- Aggressive treatment
with high dose of immunosuppressive therapy along with corticosteroids
are needed.
- In contrast to other autoimmune diseases, there
is universally no maximum age up to when pediatric SLE rather than adult SLE is
diagnosed. The disease onset is much more aggressive with a higher frequency of
major organ involvement at the time of diagnosis.
- Lupus presents
in childhood in 15% – 20% of cases. SLE is rare in children although around 20%
of all cases of SLE will have onset before adulthood.
- The
incidence of cSLE is reported to
be 630 per
100 000 children per
year.
- In cSLE,
the female to male ratio is around 5 :1 in contrast to the 9 :1 ratio seen in
adults.
- Five year
survival is currently between 90% and 95%.
- Aggressive treatment
with high dose of immunosuppressive therapy along with corticosteroids
are needed.